Table 3. Acute Adverse Effects Measured Using World Health Organization Criteria for the Chemotherapy Plus Radiotherapy (RT) Arm and the Chemotherapy-Alone Arm.
| Variable | No. (%) | |
|---|---|---|
| Chemotherapy + RT (n = 75) |
Chemotherapy Alone (n = 45) |
|
| Nausea or vomiting | ||
| Grade 2 | 46 (61.3) | 11 (24.4) |
| Grade 3 | 28 (37.3) | 25 (55.6) |
| Grade 4 | 1 (1.3) | 0 |
| Diarrhea | ||
| Grade 2 | 44 (58.7) | 6 (13.3) |
| Grade 3 | 15 (20.0) | 9 (20.0) |
| Grade 4 | 1 (1.3) | 0 |
| Abdominal paina | ||
| Grade 2 | 48 (64.0) | NA |
| Grade 3 | 2 (2.7) | NA |
| Grade 4 | 0 | NA |
| Tenesmusa | ||
| Grade 2 | 15 (20.0) | NA |
| Grade 3 | 6 (8.0) | NA |
| Grade 4 | 4 (5.3) | NA |
| Liver injury | ||
| Grade 2 | 2 (2.7) | 2 (4.4) |
| Grade 3 | 0 | 0 |
| Grade 4 | 0 | 0 |
| Kidney injury | ||
| Grade 2 | 2 (2.7) | 9 (20.0) |
| Grade 3 | 4 (5.3) | 0 |
| Grade 4 | 0 | 0 |
| Anemia | ||
| Grade 2 | 28 (37.3) | 16 (35.6) |
| Grade 3 | 20 (26.7) | 4 (8.9) |
| Grade 4 | 3 (4.0) | 0 |
| Neutropenia | ||
| Grade 2 | 9 (12.0) | 9 (20.0) |
| Grade 3 | 1 (1.3) | 4 (8.9) |
| Grade 4 | 0 | 0 |
| Thrombocytopenia | ||
| Grade 2 | 1 (1.3) | 0 |
| Grade 3 | 2 (2.7) | 0 |
| Grade 4 | 0 | 0 |
Abbreviation: NA, not applicable.
a
Adverse effects not recorded for the chemotherapy-alone arm.