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. 2018 Jan 9;319(2):154–164. doi: 10.1001/jama.2017.19130

Table 1. Overall and Subtype-Specific Breast Cancer Mortality Reductions in 2012 Associated With Screening, Treatment, or Both by Modela.

Model Mortality Reduction, %b Fraction of Combined Mortality Reduction, % Relative Contribution to Combined Mortality Reduction, %c
Associated With Screening Alone Associated With Treatment Alone Associated With Screening and Treatmentd Associated With Screening Alonee Associated With Treatment Alonef Associated With Screeningg Associated With Treatmenth
Overall
Dana-Farber 29 28 49 59 57 51 49
Erasmus 18 30 43 41 70 37 63
Georgetown-Einstein 25 37 53 47 69 40 60
MD Anderson 17 29 39 44 73 38 62
Stanford 18 37 50 36 74 33 67
Wisconsin-Harvard 17 49 58 30 84 26 74
Mean 21 35 49 43 71 37 63
By Molecular Subtype
ER+/ERBB2
Dana-Farber 30 30 52 59 58 50 50
Erasmus 18 34 46 39 73 35 65
Georgetown-Einstein 26 39 54 48 71 40 60
MD Anderson 17 31 42 42 75 36 64
Stanford 19 41 53 35 77 31 69
Wisconsin-Harvard 16 51 59 27 86 24 76
Mean 21 38 51 42 73 36 64
ER+/ERBB2+
Dana-Farber 27 38 57 46 67 41 59
Erasmus 20 42 52 39 82 32 68
Georgetown-Einstein 24 43 58 41 74 36 64
MD Anderson 18 38 46 38 82 32 68
Stanford 17 58 66 26 88 23 77
Wisconsin-Harvard 19 62 71 26 87 23 77
Mean 21 47 58 36 80 31 69
ER−/ERBB2+
Dana-Farber 25 28 49 52 58 47 53
Erasmus 17 28 41 40 68 37 63
Georgetown-Einstein 25 32 52 48 62 43 57
MD Anderson 15 23 33 45 70 39 61
Stanford 17 25 40 42 63 40 60
Wisconsin-Harvard 23 43 55 41 79 34 66
Mean 20 30 45 45 67 40 60
ER−/ERBB2
Dana-Farber 26 20 40 66 50 57 43
Erasmus 17 22 35 47 64 43 57
Georgetown-Einstein 24 29 46 53 63 45 55
MD Anderson 18 14 27 65 52 56 44
Stanford 18 17 33 53 50 52 48
Wisconsin-Harvard 18 30 42 43 70 38 62
Mean 20 22 37 55 58 48 52

Abbreviations: ER, estrogen-receptor; ERBB2; human epidermal growth factor receptor 2.

a

The column labels are defined as follows:

b

Relative to the estimated baseline mortality in 2012.

c

These columns sum to 100%.

d

Combined mortality reduction.

e

Column 2 divided by column 4.

f

Column 3 divided by column 4.

g

Column 2 divided by the sum of columns 2 and 3.

h

Column 3 divided by the sum of columns 2 and 3.