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. 2018 Feb 2;9(2):146. doi: 10.1038/s41419-017-0177-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a The criteria for defining the expression level of RAP80 in the tissue microarray (TMA), detected by IHC staining, based on the percentage of cells with different staining intensities at two magnifications (50 and 100 μm). b The Pearson χ² test of RAP80 in esophageal normal tissues (n = 83) and tumor tissues (n = 103). *p = 0.019. c The representative pictures of RAP80 staining in TMA. Scale bar, 50 and 100 μm, respectively