Skip to main content
. 2018 Feb 23;9(3):323. doi: 10.1038/s41419-018-0377-4

Fig.7. NF-κB activation is required for hepatocyte CXCL1 production.

Fig.7

Male B6 mice (6–10 weeks) were treated with live cells, necrotic cells or necrotic cells with TNF-α blocking antibody pretreatment. a Liver samples were obtained and stained with NF-κB P65 antibody, arrows indicated NF-κB P65 nuclear staining in hepatocytes. Magnification ×200 and ×400. Control or NF-κB inhibitor Celastrol (100 µg/kg) was injected 3 h before necrotic cells treatment, total blood neutrophil number (b), and neutrophil percentage (c) were determined 1 h after necrotic cells treatment. Data are expressed as mean ± SEM, n = 6 per group. **P < 0.01, ***P < 0.001