Fig. 5. Aberrant expression of let-7c enhances metastasis in vivo.
Live imaging of a distant metastasis model of lentivirus-transduced TFK-1 cholangiocarcinoma cells (a) and HUCCT-1 cells (b). c, d Body weights per mouse of the distant metastasis model. e Live imaging of distant metastasis model of lentivirus-transduced TFK-1 cholangiocarcinoma cells. f Body weights per mouse of the distant metastasis model. *P < 0.05; BC blank control group; NC negative control group; 7C+ let-7c-upregulated group; 7c− let-7c-downregulated group; miR-99a+ miR-99a-upregulated group; miR-125b-2+ miR-125b-2-upregulated group
