Table 1.
USP4 expression and clinicopathological characteristics in HCC (n = 80)
| USP4 expression | |||
|---|---|---|---|
| Low (26) | High(54) | P* | |
| Sex | |||
| Male | 23 | 45 | 0.789 |
| Female | 3 | 9 | |
| Age, years | |||
| ≤50 | 12 | 28 | 0.633 |
| >50 | 14 | 26 | |
| Tumor differentiation | |||
| I–II | 15 | 12 | 0.002 |
| III–IV | 11 | 42 | |
| Tumor encapsulation | |||
| Present | 20 | 32 | 0.121 |
| Absent | 6 | 22 | |
| Tumor size, cm | |||
| ≤5 | 19 | 20 | 0.003 |
| >5 | 7 | 34 | |
| Tumor number | |||
| Single | 17 | 46 | 0.043 |
| Multiple | 9 | 8 | |
| Vascular invasion | |||
| No | 19 | 20 | 0.003 |
| Yes | 7 | 34 | |
| Liver cirrhosis | |||
| No | 8 | 29 | 0.061 |
| Yes | 18 | 25 | |
| HBsAg | |||
| − | 2 | 6 | 0.937 |
| + | 24 | 48 | |
| Serum AFP, ng/mL | |||
| ≤20 | 11 | 10 | 0.024 |
| >20 | 15 | 44 | |
| Serum ALT, U/L | |||
| ≤75 | 23 | 50 | 0.849 |
| >75 | 3 | 4 | |
| Serum TB, μmol/L | |||
| ≤17 | 16 | 42 | 0.128 |
| >17 | 10 | 12 | |
*Pearson’s chi-square test was used. P < 0.05 was considered statistically significant