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. 2018 Feb 19;9(3):287. doi: 10.1038/s41419-018-0331-5

Fig. 5. mRNA expression levels of oxidative stress defense proteins in light-exposed RPE cells.

Fig. 5

We measured the mRNA expression levels for SOD1 a, SOD2 b, catalase c, and GPX1 d proteins in RPE cells after 15 h of light exposure in the presence or absence of A2E (20 µM). All values were normalized to the expression level of ribosomal 18S RNA under the same experimental conditions and then normalized to the expression levels of RPE cells maintained in darkness without A2E. n = 3. Differences between samples and dark controls were considered to be significant when p < 0.05 (▲/*), p < 0.01 (▲▲/**), or p < 0.001 (▲▲▲/***). Triangles (▲) refer to the difference with the untreated dark control and stars (*) to A2E-treated dark control. Each 10 nm spectral band is designated by its central wavelength