Fig. 6. ALCAM expression is correlated with the prognosis of clinical GCTB cases.

a–d Representative immunohistochemical staining of ALCAM in human GCTB tissues. The cytomembrane staining of ALCAM was categorized and represented as follows: A, score 0; B, score 1; C, score 2; D, score 3. e Compared to that in corresponding adjacent tissues, the mRNA expression of ALCAM was higher in 28 primary GCTB samples. Independent experiments were repeated three times. Data were presented as mean ± s.d. (t-test, ***p < 0.001; **p < 0.01; *p < 0.05). f Kaplan–Meier survival curves of overall survival (OS) and disease-free survival (DFS) measured according to the ALCAM expression, Enneking stages and Jaffe stages in clinical GCTB samples