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. 2018 Jan 24;9(2):86. doi: 10.1038/s41419-017-0157-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a REC-1 and MAVER-1 cells were stimulated with CD40L (100 ng/ml) or H₂O as a control for 18 h, and cytoplasmic (Cy) and nuclear (Nu) protein fractions were analyzed by Western blot. α-Tubulin and lamin B served as controls for the purity of the individual cell compartment fractions. b MCL cell lines were stimulated with CD40L (100 ng/ml) or H₂O as a control overnight followed by TPCA-1 treatment at the indicated concentration. After an additional 24 h, viability was determined by MTT assay (*p < 0.001; **p < 0.0001; ***p < 0.00001)