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. 2018 Feb 15;9(3):253. doi: 10.1038/s41419-018-0305-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A The photography of xenograft tumors from Balb/C null mouse injected with Hep3B cells transfected with pCMV6-A-GFP, pCMV6-A-GFP-MEG3 subcutaneously in the armpit. B The xenograft tumors weight (gram) in the four groups indicated in left. Data are means of values from nine Balb/c mice, mean ± SEM, n = 5, *, P < 0.05; **, P < 0.01. C A portion of each xenograft tumor was fixed in 4% formaldehyde and embedded in paraffin, and micrometers of sections (4 µm) were made for hematoxylin–eosin (HE) staining (original magnification ×100), and anti-PCNA and anti-k67 immunostainning in xenograft tumor samples (original magnification ×100)