Table 1.

Inflammatory mediators involved in functional and structural impairment of neurons

Inflammatory mediators	Experimental setup	Effect	Reference
TNFalpha	Slice culture	LTP suppression	Tancredi et al., 199242
IL-1beta	In vivo recording	LTP suppression	Murray & Lynch, 199844
NO	Slice culture	LTP suppression	Wang et al., 200438
IL-6	Slice culture	LTP suppression	Tancredi et al., 200043
C3	Slice culture	LTP suppression	Lian et al., 201545
IL-1alpha, TNFalpha, C1q	Cell culture and in vivo axotomy model	Neuronal death via astrocyte activation	Liddelow et al., 201778