Table 2.
GO enrichment analysis of some ischemic stroke-related lncRNAs
| LncRNA | GO category | GO term |
|---|---|---|
| MEG3 | Biological process | DEVELOPMENT: lung development; embryo development; post-embryonic development; skeletal muscle development; liver development; multicellular organism growth; determination of adult lifespan. |
| VASCULAR: angiogenesis; regulation of vascular endothelial growth factor receptor signaling pathway; | ||
| GENE REGULATION: RNA folding; DNA-templated transcription; DNA biosynthesis; hypomethylation of CpG island; DNA methylation; genetic imprinting. | ||
| INFLAMMATION: Notch signaling pathway; SMAD protein signal transduction. | ||
| CELL GROWTH: cell differentiation; negative regulation of cell proliferation. | ||
| OTHERS: axon guidance; gonadotropin secretion; epithelial tube morphogenesis. | ||
| Molecular function | Transcription co-activator activity. | |
| Cellular component | Nucleus, cytoplasm. | |
| MALAT1 | Biological process | Nuclear speck organization; mRNA splicing; synapse organization; myoblast proliferation. |
| Molecular function | Protein binding. | |
| Cellular component | Nuclear body, nuclear speck. | |
| H19 | Biological process | GENE REGULATION: DNA methylation; gene expression; genetic imprinting. |
| CELL GROWTH: regulation of multicellular organism growth; regulation of cell proliferation. | ||
| Cellular component | Polysome, cytoplasm. | |
| TUG1 | Biological process | Photoreceptor cell development. |