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. 2018 Jan 16;9(2):16. doi: 10.1038/s41419-017-0045-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Transfection of IGF2BP2 siRNA significantly reduced HTR-8/SVneo cell invasion and migration, with effects similar to those of miR-181a-5p overexpression. Representative fields of invaded/migrated cells (at 200× original magnification, bar = 10 μm) are shown. b The IGF2BP2 mRNA/protein levels were examined after siRNA transfection. A representative western blotting image with the molecular weight markers depicted on the left in kDa is shown. c Ectopic-expression of IGF2BP2 significantly promoted HTR-8/SVneo cell invasion and migration. Representative fields of invaded/migrated cells (at 200× original magnification, bar = 10 μm) are shown. d The IGF2BP2 mRNA/protein levels were examined after plasmid transfection. A representative western blotting image with the molecular weight markers depicted on the left in kDa is shown. The results are expressed as the mean ± SD based on at least three independent experiments. *P < 0.05; **P < 0.01