Table 1.
IC50 (TMZ: μM) | ||||
---|---|---|---|---|
– | F: 0.4 μM | F: 2 μM | F: 10 μM | |
U251R | 4189.00 ± 922.61 | 853.66 ± 210.39* | 440.26 ± 55.41** | 244.7 ± 56.01** |
U87R | 3262.00 ± 1079.21 | 1326.66 ± 310.68* | 1566.66 ± 269.78** | 176.16 ± 40.08* |
T5R | 1731.33 ± 363.08 | 705.16 ± 107.80* | 574.20 ± 172.59** | 150.50 ± 44.17* |
T6R | 5178.66 ± 957.04 | 407.63 ± 150.78* | 198.76 ± 69.30* | 101.93 ± 14.55* |
rG-1 | 2868.66 ± 350.48 | 852.36 ± 214.80* | 213.36 ± 161.17** | 86.53 ± 32.96* |
U87 neurospheres | 3629.66 ± 354.45 | 2143.66 ± 905.64 | 1128.66 ± 123.71* | 236.43 ± 47.08** |
Statistical differences compared with the control group (U251/U87/T5/T6/C6) is given as *P < 0.05, **P < 0.01