Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 8;9(2):200. doi: 10.1038/s41419-017-0173-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a Scatter plot of the differential gene expression between the control and ATRA-treated HL-60 cells. Red dots denote genes with significantly upregulated expression in the ATRA-treated cells (log2(foldchange)>0.9, adjusted p-value < 0.01). Blue dots denote genes with significantly downregulated expression in the ATRA-treated cells (log2(foldchange)<−0.9, adjusted p-value < 0.01). Gray dots denote genes with no significant expression change. b Top 10 GO terms of differentially expressed genes between the control and ATRA-treated HL-60 cells. FDR false discovery rate. c Probability density of TADs with at least one gene expression change based on the internal Hi-C counts. σ represents the standard deviation of all TAD log2 internal Hi-C counts. d Accumulation bar-plot showing the enrichment of genes in TADs. The TADs are divided into seven categories as shown in Fig. 2c, and total represents all expressed genes located in TADs. Number of genes located in each type of TAD is shown above the bar