Table 1.
Correlation between expression of p-AMPK (Thr 172) and clinicopathological characteristics in Chongqing and West China cohort
| Chongqing cohort | West China cohort | |||||
|---|---|---|---|---|---|---|
| p-AMPK(low) | p-AMPK(High) | P value | p-AMPK(low) | p-AMPK(High) | P value | |
| N | 94 | 332 | 27 | 104 | ||
| Gender (M) | 69(73.4) | 245(73.8) | 0.939 | 18(66.7) | 64(61.5) | 0.624 |
| Age | 46.2 ± 10.9 | 46.4 ± 11.1 | 0.905 | 48.5 ± 13.8 | 46.3 ± 12.3 | 0.409 |
| Etiology | 0.066 | |||||
| HBV | 73(77.7) | 292(88.0) | 27(100) | 104(100) | ||
| HCV | 3(3.1) | 9(2.7) | ||||
| NAFLD | 7(7.4) | 14(4.2) | ||||
| Alcohol | 4(4.2) | 9(2.7) | ||||
| Unclear | 7(7.4) | 8(2.4) | ||||
| Child-pugh | 0.024 | 0.929 | ||||
| A | 33(35.1) | 142(42.8) | 13(48.1) | 54(51.9) | ||
| B | 48(51.1) | 171(51.5) | 13(48.1) | 47(45.2) | ||
| C | 13(13.8) | 19(5.7) | 1(3.7) | 3(2.9) | ||
| ALT(IU/L) | 53.9 ± 38.6 | 53.6 ± 43.4 | 0.994 | 59.6 ± 33.9 | 41.5 ± 29.4 | 0.007 |
| AST(IU/L) | 67.2 ± 48.0 | 65.3 ± 49.2 | 0.741 | 67.519 ± 42.845 | 53.3 ± 37.0 | 0.088 |
| GGT(IU/L) | 72.3 ± 58.0 | 69.1 ± 59.3 | 0.646 | 81.963 ± 54.886 | 70.4 ± 63.5 | 0.39 |
| AFP(μg/L) | 34.9 ± 74.2 | 32.9 ± 73.4 | 0.811 | 23.584 ± 27.272 | 26.4 ± 48.6 | 0.772 |
| TBIL(μmol/L) | 42.9 ± 48.8 | 35.9 ± 36.5 | 0.318 | 44.311 ± 58.939 | 30.1 ± 27.8 | 0.913 |
| ALB(g/dL) | 3.7 ± 0.7 | 3.7 ± 0.6 | 0.817 | 3.775 ± 0.523 | 3.7 ± 0.6 | 0.731 |
| Ascite | 22(23.4) | 72(21.7) | 0.723 | 6(22.2) | 21(20.2) | 0.816 |
| Hepatic encephalopathy | 1(1.1) | 3(0.9) | 1.000 | 1(3.7) | 0(0) | 0.206 |
| Diabetes mellitus | 38(40.4) | 98(29.5) | 0.045 | 8(29.6) | 31(29.8) | 0.986 |
| Alcohol | 22(23.2) | 76(22.9) | 0.917 | 5(18.5) | 20(19.2) | 0.933 |
| GI bleeding | 59(62.8) | 113(34.0) | <0.001 | 7(25.9) | 41(39.4) | 0.195 |