Table 3.
Overall survival | ||||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age (years) | ||||
<65 | – | |||
≥65 | 0.830 (0.509–1.355) | 0.457 | ||
Gender | ||||
Male | – | |||
Female | 0.753 (0.444–1.277) | 0.292 | ||
Tumor location | ||||
Gastric fundus | – | |||
Gastric corpus | 1.089 (0.496–2.393) | 0.832 | ||
Pylorus | 4.034 (0.478–34.077) | 0.200 | ||
Tumor sizes (cm) | ||||
<3 | – | |||
≥3 | 1.285 (0.467–3.537) | 0.627 | ||
T stage | ||||
T1 | – | |||
T2 | 0.863 (0.215–3.460) | 0.835 | ||
T3 | 3.457 (1.209–9.883) | 0.021 | ||
T4 | 3.770 (1.190–11.942) | 0.024 | ||
N stage | ||||
N0 | – | |||
N1 | 1.540 (0.764–3.100) | 0.227 | ||
N2 | 2.616 (1.302–5.255) | 0.007 | ||
N3 | 0.000 (0.000–0.000) | 0.969 | ||
M stage | ||||
M0 | – | |||
M1 | 2.562 (1.218–5.391) | 0.013 | ||
UICC stage | ||||
I | – | |||
II | 4.521 (1.032–19.798) | 0.045 | ||
III | 9.787 (2.298–41.671) | 0.002 | ||
IV | 13.481 (2.833–64.142) | 0.001 | ||
Vessel invasion | ||||
No | – | |||
Yes | 1.194 (0.649–2.196) | 0.568 | ||
Nerve invasion | ||||
No | – | |||
Yes | 0.861 (0.269–2.759) | 0.802 | ||
Differentiation | ||||
High | – | |||
Moderate | 1.488 (0.201–11.013) | 0.697 | ||
Low | 1.838 (0.251–13.478) | 0.550 | ||
Relapse | ||||
No | – | |||
Yes | 2.550 (1.521–4.276) | <0.001 | ||
PCDHGA9 | ||||
Negative | – | – | ||
Weak | 0.522 (0.301–0.905) | 0.021 | 0.461 (0.225–0.946) | 0.035 |
Positive | 0.013 (0.002–0.104) | <0.001 | 0.003 (0.000–0.050) | <0.001 |
HR hazard ratio, CI confidence interval