Table 4.

Univariate and multivariate analyses for pathologic complete response (pCR) and pathological partial response (pPR) according to patient and treatment variables.

Variable	pCR		pPR
	Univariate	Multivariate	Univariate	Multivariate
	p valuea	p valueb	p valuea	p valueb
Gender	ns	–	ns	–
Stage
II	p < 0.001	ns	p < 0.001	p < 0.001
III*
Dose*	p = 0.002	ns	p = 0.01	p = 0.006
Chemotherapy schedule
1 drug	ns	–	p = 0.04	p = 0.01
2-drug*
Time interval*	p < 0.001	p < 0.001	p < 0.001	p = 0.001

^aSignificant p values (p value <= 0.05) are in bold.

^bOnly variables with a p value ≤0.05 in the univariate logistic regression analysis were included in the multivariate model.

^*stage III, higher dose, 2-drug schedule and longer interval correlated with better pathological response. Dose and time interval were considered as continuous variables in the logistic regression analysis.