Table 4.
Multivariate analysis of variables associated with overall survival in patients treated with external beam radiation for hepatocellular carcinoma portal vein tumor thrombus.
| HR | 95% CI | P-value | |
|---|---|---|---|
| KPS at EBRT | .087 | ||
| >80 | Reference | Reference | |
| ≤80 | 2.29 | 0.89–6.14 | |
| N-stage | .295 | ||
| N0 | Reference | Reference | |
| N1 | 2.04 | 0.52–7.24 | |
| Radiation dose as a continuous variable* | 1.04 | 0.96–1.13 | .393 |
| Radiation dose | .133 | ||
| ≤55 Gy | Reference | Reference | |
| >55 Gy | 0.39 | 0.10–1.31 | |
| BED as a continuous variable* | 1.03 | 0.99–1.06 | .058 |
| BED | .015 | ||
| ≤75 Gy | Reference | Reference | |
| >75 Gy | 0.10 | 0.01–0.66 |
EBRT = external beam radiotherapy; KPS = Karnofsky Performance Status; BED = biologically effective dose; Gy = Gray.
*
HR listed is per Gy.