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. Author manuscript; available in PMC: 2018 Mar 2.
Published in final edited form as: Nat Mater. 2013 Apr 21;12(6):576–583. doi: 10.1038/nmat3627

Figure 3. Histogram describing the prevalence of dense calcium- and phosphorus-containing structures on the surface of aortic valves (AV).

Figure 3

Representative images of AV are categorized by presence and extensiveness of calcific lesions. Sampled regions indicated in circles. Category a is comprised of AV that did not present any macroscopically observable calcific lesions on AV or in surrounding tissue (aorta and coronary arteries). b represents AV without macroscopically observable calcification on AV, but with macroscopically observable calcific lesions on surrounding tissues. c includes analyses carried out on non-calcified areas of AV which presented calcific lesions in other areas of the AV. d includes analyses carried out on non-calcified areas of AV which were heavily calcified in other areas. e identifies structures on macroscopically observable calcific lesions. f includes analyses carried out on calcific lesions from heavily calcified AV. Approximately 350 images were obtained from each of the 55 regions examined in AV from 32 patients.