Figure 5.
a) Alkaline phosphatase activity of Saos-2 cells cultured on the surface of BG discs for 7, 14 and 28 days. * indicates significantly higher ALP activity per cell in the indicated group compared to Saos-2 on 0 mol% CaF2 discs at the same time point. b) Alkaline phosphatase activity of Saos-2 cells exposed to the dissolution products of BG discs after 7, 14 and 28 days in culture. * significantly higher ALP activity compared to all other groups at the same time point. + significantly higher ALP activity than the 0 mol% CaF2 group at same time point. ‡ significantly higher ALP activity than the 4.75 mol% CaF2 group at same time point. † significantly higher ALP activity than 9.28 mol% CaF2 group at same time point. # significantly higher ALP activity than 13.62 mol% CaF2 group at the same time point.