. Author manuscript; available in PMC: 2018 Mar 2.

Published in final edited form as: J Nutr. 2007 Dec;137(12):2647–2652. doi: 10.1093/jn/137.12.2647

Table 1.

Plateau enrichments of stable isotope-labeled amino acids and their metabolic products and the corresponding flux values in healthy men and women ¹

	Plateau enrichment (Ep) [mol % excess]	Whole Body Flux (Q) [μmol/(kg·h)]
Infused amino acids (AA)		Q_{infused AA}
[²H₃]leucine	1.82 ± 0.13	102 ± 7
[¹³C₂]glycine	5.10 ± 0.72	463 ± 55

Metabolic products
		Q_{Gly→Ser M+x}
[¹³C₁]serine (Ser M+1) ²	0.63 ± 0.05	88 ± 13
[¹³C₂]serine (Ser M+2) ³	1.39 ± 0.07	193 ± 28
		Q_Gly→CO₂
[¹³CO₂]	0.037 ± 0.012	190 ± 41

Values are means ± SEM, n=5.

Serine synthesis via SHMT using a glycine-derived one-carbon unit.

Serine synthesis from glycine via SHMT.