Table 1.
Top signatures for ADC and SCC patients
| No. of genes | HR (95% CI) | Q | P value | |
|---|---|---|---|---|
| ADC patients | ||||
| Chen2 | 92 | 1.69 (1.56–1.83) | 63.29 | 5.54E−16 |
| Shedden_c | 452 | 1.72 (1.56–1.89) | 51.73 | 5.55E−14 |
| Kadara | 5 | 1.67 (1.53–1.81) | 59.15 | 2.70E−13 |
| Tomida1_a | 23 | 1.41 (1.30–1.52) | 62.49 | 4.63E−08 |
| Lu1 | 62 | 1.47 (1.33–1.63) | 81.93 | 8.68E−08 |
| Xie | 59 | 1.54 (1.42–1.66) | 67.27 | 1.15E−07 |
| Bianchi | 10 | 1.46 (1.32–1.62) | 81.69 | 3.41E−07 |
| Tang | 18 | 1.39 (1.27–1.53) | 45.50 | 2.58E−06 |
| Matsuyama | 169 | 1.42 (1.30–1.54) | 65.50 | 8.94E−06 |
| Sun_a | 46 | 1.34 (1.24–1.45) | 53.51 | 2.69E−05 |
| Bhattacharjee | 151 | 1.39 (1.27–1.51) | 47.96 | 0.000113 |
| Parmigiani | 14 | 1.33 (1.22–1.45) | 54.03 | 0.001416 |
| Raponi_b | 45 | 1.30 (1.21–1.41) | 49.89 | 0.001657 |
| Beer | 95 | 1.28 (1.18–1.38) | 62.77 | 0.002085 |
| Tomida1_c | 11 | 1.25 (1.15–1.35) | 75.89 | 0.00560 |
| Fujiwara | 70 | 1.25 (1.13–1.38) | 104.52 | 0.0110 |
| Sun_b | 43 | 1.25 (1.15–1.36) | 82.50 | 0.0143 |
| SCC patients | ||||
| Shedden_d | 332 | 1.41 (1.25–1.59) | 84.41 | 2.19E−11 |
| Raponi_b | 45 | 1.29 (1.15–1.44) | 50.99 | 1.54E−05 |
| Kadara | 5 | 1.21 (1.10–1.34) | 37.02 | 2.96E−05 |
| Roepman | 66 | 1.27 (1.13–1.44) | 65.38 | 3.40E−05 |
| Parmigiani | 14 | 1.23 (1.12–1.36) | 48.70 | 6.86E−05 |
| Chen2 | 92 | 1.18 (1.07–1.30) | 57.93 | 0.000130 |
| Tang | 18 | 1.18 (1.07–1.29) | 24.98 | 0.000444 |
| Mitra | 4 | 1.20 (1.05–1.37) | 47.30 | 0.00581 |
Information included are number of genes in the signatures, meta-estimated hazard ratios (HR), and 95% confidence intervals for the predicted high risk groups, Q-statistics for heterogeneity from meta-analysis, and P-values for comparison to random signatures.