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. 2016 Dec 28;28(4):696–701. doi: 10.1093/annonc/mdw681

Table 4.

Summary data (by stage and combined current total) of partially completed Mel 63 trial

Stage Total Regimen Toxicity Immune response
Accrual (n) # of DLT/# treated # of dRsp/# treated
1 2 A 0/2 0/2
1 2 B 0/2 1/2
1 2 C 0/2 0/2
1 2 D 1/2 2/2
2 1 A 0/1 0/1
2 5 B 1/5 1/5
2 4 C 0/4 4/4
2 12 D 0/12 10/12
1 + 2 3 A 0 (0%) 0 (0%)
1 + 2 7 B 1 (14%) 2 (29%)
1 + 2 6 C 0 (0%) 4 (67%)
1 + 2 14 D 1 (7%) 12 (86%)