Table 4.
Summary data (by stage and combined current total) of partially completed Mel 63 trial
Stage | Total | Regimen | Toxicity | Immune response |
---|---|---|---|---|
Accrual (n) | # of DLT/# treated | # of dRsp/# treated | ||
1 | 2 | A | 0/2 | 0/2 |
1 | 2 | B | 0/2 | 1/2 |
1 | 2 | C | 0/2 | 0/2 |
1 | 2 | D | 1/2 | 2/2 |
2 | 1 | A | 0/1 | 0/1 |
2 | 5 | B | 1/5 | 1/5 |
2 | 4 | C | 0/4 | 4/4 |
2 | 12 | D | 0/12 | 10/12 |
1 + 2 | 3 | A | 0 (0%) | 0 (0%) |
1 + 2 | 7 | B | 1 (14%) | 2 (29%) |
1 + 2 | 6 | C | 0 (0%) | 4 (67%) |
1 + 2 | 14 | D | 1 (7%) | 12 (86%) |