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Genetic risk score of discovery set for SNPs of significantly mutated genes in lung cancer (MD Anderson, n = 3142)
| Risk score | Cases, n (%) | Controls, n (%) | ORa(95% CI) | P |
|---|---|---|---|---|
| ≤0.90 | 301 (44.79) | 371 (55.21) | 1 (Reference) | |
| 0.91–1.16 | 414 (51.56) | 389 (48.44) | 1.40 (1.12–1.76) | 2.8 × 10−3 |
| 1.17–1.35 | 419 (54.13) | 355 (45.87) | 1.58 (1.26–1.98) | 6.3 × 10−5 |
| >1.35 | 521 (58.61) | 368 (41.39) | 1.90 (1.53–2.37) | 8.4 × 10−9 |
| P for trend | 9.5 × 10−9 |
Adjusted for age, gender and smoking status.
