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Kaplan–Meier curves for OS (without censoring at crossover) for patients with (A) ECOG PS 0, (B) ECOG PS 1, (C) LDH level normal and (D) LDH level elevated. CI, confidence interval; DTIC, dacarbazine; ECOG PS, Eastern Cooperative Oncology Group performance status; LDH, lactate dehydrogenase; OS, overall survival. Vem, vemurafenib.
