Table 1. Patient demographics, clinical features and cell line designations.
Cell Line Designation | Location | Histologya,[15] | Primary Treatment | Treatment at Recurrence | Overall Survival (Months) |
---|---|---|---|---|---|
GS1 | Right fronto-temporal | Gliosarcoma | Surgical resection | N/A | 4.3 |
TS1 | Left frontal & thalamic | Gliomatosis cerebri | Biopsy only | N/A | 1.3 |
TS6 | Right frontal | GBM | Surgical resection + TMZ +Irradiation | PCV | 9.2 |
TS9 | Left frontal | Recurrent GBM | Surgical resection + TMZ +Irradiation | Surgical resection +PCV | 14.3 |
TS17 | Right occipital | GBM | Surgical resection | N/A | 0.9 |
TS18 | Left parietal | GBM | Surgical resection | N/A | 5.6 |
TS20 | Left frontal | GBM | Surgical resection + TMZ +Irradiation | N/A | 8.4 |
aHistological diagnoses were made prior to the WHO 2016 re-classification. Gliomatosis cerebri is now referred to as a rare diffuse-pattern glioblastoma and gliosarcoma has been incorporated into the umbrella term IDH-wildtype glioblastoma.