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. 2018 Feb 27;13:1119–1137. doi: 10.2147/IJN.S147464

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© 2018 Pan et al. This work is published and licensed by Dove Medical Press Limited

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Antitumor efficacy of targeting-active and external magnetic nanoparticles in vivo. (A) Tumor growth curve of PBS, DOX, DOX@IONPs, FA-DOX@IONPs, DOX@IONPs plus magnetic treatment, and FA-DOX@IONPs plus magnetic treatment. *p<0.05 is considered to be a statistically significant difference (n=3). (B) The body weight changes with the treatments for 24 days. (C) Tumor size on the 24th day after treatment of PBS, DOX, DOX@IONPs, FA-DOX@IONPs, and DOX@IONPs plus magnetic treatment.

Abbreviations: DOX, doxorubicin; FA, folic acid; IONP, iron oxide nanoparticle.