Table 3. Subgroup analysis for incidence rates and hazard ratios (HR) of overactive bladder between patients with and without idiopathic Parkinson’s disease, stratified by sex, age, and comorbidity status.
| Characteristics | Idiopathic Parkinson’s disease | HR (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|
| Yes | No | Univariate | Multivariate& | |||||
| Event | PY | Rate# | Event | PY | Rate# | |||
| Sex | ||||||||
| Female | 19 | 11597 | 16.4 | 37 | 49078 | 7.54 | 2.19(1.26, 3.81)** | 2.19(1.26, 3.81)** |
| Male | 14 | 11120 | 12.6 | 25 | 48250 | 5.18 | 2.47(1.28, 4.76)** | 2.47(1.29, 4.76)** |
| Age, year | ||||||||
| ≤64 | 5 | 5151 | 9.71 | 12 | 21735 | 5.52 | 1.77(0.62, 5.03) | 1.79(0.63, 5.08) |
| 65–74 | 19 | 8730 | 21.8 | 23 | 37375 | 6.15 | 3.63(1.98, 6.67)*** | 3.65(1.99, 6.71)*** |
| 75–84 | 9 | 7713 | 11.7 | 23 | 33556 | 6.85 | 1.71(0.79, 3.70) | 1.72(0.79, 3.72) |
| ≥85 | 0 | 1123 | 0.00 | 4 | 4662 | 8.58 | - | - |
| Comorbidity§ | ||||||||
| No | 17 | 14139 | 12.0 | 31 | 61179 | 5.07 | 2.44(1.35, 4.41)** | 2.44(1.35, 4.41)** |
| Yes | 16 | 8578 | 18.7 | 31 | 36149 | 8.58 | 2.18(1.19, 3.98)* | 2.18(1.19, 3.98)* |
CI: confidence interval.
Rate#: incidence rate, per 10,000 person-years.
&: multivariate analysis including comorbidities of benign prostate hyperplasia, and stress incontinence.
§: subjects with any comorbidity of benign prostate hyperplasia, stress incontinence, diabetes, or cerebrovascular diseases were classified into the comorbidity group.
*p<0.05.
**p<0.01.
***p<0.001.