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. 2018 Jan 19;9(13):11126–11144. doi: 10.18632/oncotarget.24277

Figure 1. Sema4D expression in different clinical stages of HNSCC.

Figure 1

(A) IHC shows Sema4D-ve/low expression in tumor cells of a stage I SCC of the nasal cavity. (B) Sema4D-ve/low expression in tumor cells of Stage II SCC of the larynx. Moderate stromal infiltration with Sema4D+ve/high TAIs. (C) Sema4D+ve/high expression in tumor cells of a stage III SCC of the upper Jaw. (D) Sema4D-ve/low expression in tumor cells of stage IV SCC of the gingiva with the peri-tumoral stroma showing heavy infiltration of Sema4D+ve/high TAIs. (20x; 200um scale, inset: 40x).