Table 3. PD-L1 expression in relation to tumor staging, stromal fibrosis and Sema4D expressing TAIs.
| Total PD-L1 expression in tumor cells and TAIs | Total | P-value | ||
|---|---|---|---|---|
| -ve/low No (%) | +ve/high No (%) | |||
| Tumor stage | ||||
| I+II | 38 (66) | 20 (34) | 58 (43) | 0.58 |
| III | 26 (65) | 14 (35) | 40 (30) | |
| IV | 22 (59) | 15 (41) | 37 (27) | |
| Total | 86 (64) | 49 (36) | 135 (100) | |
| Nodal metastases | ||||
| Yes | 17 (47) | 19 (53) | 36 (27) | 0.016 |
| No | 69 (70) | 30 (30) | 99 (73) | |
| Total | 86 (64) | 49 (36) | 135 (100) | |
| Stromal Fibrosis | ||||
| Delicate/moderate | 43 (57) | 32 (43) | 75 (69) | 0.14 |
| Dense | 24 (73) | 9 (27) | 33 (31) | |
| Total | 67 (62) | 41 (38) | 108 (100) | |
| Sema4D+ve/high TAIs infiltrate | ||||
| No | 29 (80) | 7 (20) | 36 (34) | 0.007 |
| Yes | 38 (54) | 33 (46) | 71 (66) | |
| Total | 67 (63) | 40 (37) | 107 (100) | |