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(A–C) Protein and mRNA expression levels of Nr4a2 were significantly decreased after treatment with Nr4a2-siRNA in CD4+ T cells from healthy control subjects (p < 0.001, p < 0.001, respectively). (D) mRNA expression levels of GATA3, IL-4, and IL-13 were significantly elevated after treatment with Nr4a2-siRNA in CD4+ T cells from healthy control subjects (p = 0.01, p < 0.001, p < 0.001, respectively). (*p < 0.05, **p < 0.01, ***p < 0.001).
