Table 1. STR profile of patients and PDTXs.
AMEL | D5S818 | D13S317 | D7S820 | VWA | TH01 | TPOX | CSF1P0 | D18S51 | D3S1358 | D8S1179 | FGA | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
patient 16 | XY | 12,13 | 13,14 | 8 | 18,19 | 8,9.3 | 11,12 | 12 | 14 | 16,18 | 12,15 | 21,22 |
Mela16 PDTX | XY | 12,13 | 13,14 | 8, 11 | 18,19 | 8,9.3 | 11,12 | 12 | 14 | 16,18 | 12,15 | 21,22 |
patient 11 | XY | 11,12 | 11,12 | 10 | 18,19 | 7,9.3 | 8 | 10,12 | 13,17 | 16 | 13,* | 21 |
Mela11 PDTX | XY | 11,12 | 11,12 | 10 | 18,19 | 7,9.3 | 8 | 10,12 | 13,17 | 16 | 13,14 | 21 |
patient 14 | XY | 12 | 11,12 | 9,11 | 16,20 | 9,9.3 | 8 | 10,12 | 10.1,14 | *,16 | 12,14 | 24,26 |
Mela14 PDTX | XY | 12 | 11,12 | 9,11 | 16,20 | 9,9.3 | 8 | 10,12 | 10.1,14 | 15,16 | 12,14 | 24,26 |
STR DNA sequences of both patient and mouse tumors validate genetic identities of developed models. a, Asterisks indicated lost allele.