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. 2018 Feb 2;9(13):11279–11290. doi: 10.18632/oncotarget.24397

Figure 2. Changes of immune-related gene expression in PBMCs in HNSCC patients after the initial two weeks of CMT.

Figure 2

PBMC samples were collected from six patients; 4 HPV+ and 2 HPV– patients, before and after two weeks of CMT to isolate mRNA. The mRNA samples were analyzed using Nanostring assay on the Human Pancancer Immune panel, followed by the data analysis in the nSolver software. The average fold changes (log2) of the 40 cytokine genes and 69 chemokine genes (A) were presented using volcano plots (A and C, respectively). The heatmap analysis of selected cytokines and chemokines are shown (B and D, respectively).