Table 1. Population demographics of each tumor type and the characteristics of the samples included in this study.

	Retinoblastoma	Medulloblastoma	Neuroblastoma
Population and clinical characteristics
Anatomical location	eye	brain (cerebellum)	sympathetic nervous system (various locations)
Mean age at diagnosis	18 months	5–6 years	2–3 years
% of all childhood cancers (0–14y) ; USAaUK b	3% (280 per year) 3% (44 new cases per year)	3.8% (400 per year) 3.5% (54 new cases per year)	7% (710 per year) 6% (78 new cases per year)
Gender distribution (F:M); Range: USAa-UK b	48–50%	60–65%	53–55%
5Y overall survival rate; Range: USAa-UK b	99%	65–71.3%	65%–79%
Characteristics of tumor samples included in this study
Sample numbers	n = 50	n = 39	n = 70
Period samples collected over	2004–2013	1999–2013	1996–2012
Mean age at diagnosis (years)	1.5	6.5	2.5
Gender distribution	37% male	75% male	60% male
5Y survival rate	100%	60%	67%

^aReported in Mathew et al., Neuro-oncology 2014 [59] ^bStatistics reported on CRUK website ^cReported in Ward et al., CA Cancer J Clin 2014 [60].