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. Author manuscript; available in PMC: 2019 Mar 2.
Published in final edited form as: Hepatology. 2018 Jan 2;67(2):676–689. doi: 10.1002/hep.29504

Figure 6. Connectome for the cholangiopathy subcore genes and STAT3, IL6, TNF and FOXP3 centered network.

Figure 6

(A) Regulatory network of subcore genes and grey edges indicating regulatory interaction obtain from transcription factor-miRNA co-regulatory network. The size of the nodes is proportional to the number of edges connected to the node. Red represents the key genes; Blue represents the genes most shared among the cholangiopathies. (B) Network linking STAT3, IL6, TNF and FOXP3 with cholangiopathy-associated genes and miRNAs. Red nodes: key genes; blue nodes: genes shared by three diseases; black nodes: genes/miRNAs for individual disease or shared by two diseases.