Table 2.
Variable | Attrition due to death | Attrition due to illness | Attrition at random (loss to follow-up) | p |
---|---|---|---|---|
N=29 (27%) | N=30 (28%) | N=48 (45%) | ||
| ||||
Age (mean; SD) | 60 (13) | 62 (13) | 60 (14) | .82† |
| ||||
Gender | .22~ | |||
Female | 11 (38) | 11 (38) | 26 (54) | |
| ||||
Marital Status | .54~ | |||
Single | 6 (21) | 4 (13) | 6 (13) | |
Married | 18 (62) | 19 (64) | 26 (54) | |
Divorced/Widowed | 5 (17) | 7 (23) | 16 (33) | |
| ||||
Cancer type | .74+ | |||
GI | 10 (34) | 10 (33) | 18 (38) | |
Breast | 2 (17) | 3 (17) | 4 (17) | |
Respiratory | 5 (17) | 4 (13) | 7 (16) | |
GU | 0 (0) | 3 (10) | 4 (8) | |
H&N | 5 (17) | 4 (13) | 5 (10) | |
GYN | 3 (10) | 1 (3) | 7 (15) | |
Hematological | 1 (3) | 1 (3) | 2 (4) | |
Other | 3 (10) | 4 (13) | 1 (2) | |
| ||||
MDAS (median; IQR)* | 2;(1–4) | 2; (1–4) | 2,5;(1–4) | .85‡ |
| ||||
ESAS (median; IQR)* | ||||
Pain (n=743) | 4.5; (.5–8) | 5; (2–7) | 5.5;(3–7) | .30‡ |
Fatigue | 6; (5–8) | 4; (2–6) | 4.5;(1–6.5) | <.001‡ |
Nausea | 0; (0–5) | 2.5; (0–5) | 0;(0–3) | .01‡ |
Depression | 5; (2–7) | 2;(0–5) | 2;(0–4.5) | .01‡ |
Anxiety | 0; (0–5) | 2;(0–5) | 3;(0–6.5) | .14‡ |
Drowsiness | 6; (3–8) | 2.5;(0–5) | 3;(0–6.5) | .01‡ |
Anorexia (n=743) | 5; (3–6) | 5.5;(3–8) | 4.5;(1–7) | .34‡ |
Wellbeing | 6; (5–8) | 5;(3–7) | 3.5;(1–5) | <.001‡ |
Dyspnea | 4; (0–7) | 1;(0–4) | 0;(0–4) | .04‡ |
Sleep | 3; (2–6) | 4;(0–6) | 2.5;(0–4.5) | .18‡ |
| ||||
ESAS physical score (mean; SD) (n = 742) | 28 (12) | 23; (11) | 19 (10) | .003† |
| ||||
ESAS emotional score (mean; SD) | 7 (5) | 5 (5) | 6 (5) | .41† |
| ||||
Time from cancer diagnosis in months (median; IQR) (n = 737) | 12; (4–21) | 16;(8–36) | 17; (5–41) | .19†∫ |
| ||||
KPS (n = 737) | .03~ | |||
90≤ | 4 (15) | 0 (0) | 8 (19) | |
80 | 1 (4) | 4 (13) | 11 (24) | |
70 | 5 (19) | 13 (44) | 10 (22) | |
60 | 7 (27) | 7 (23) | 10 (22) | |
≤50 | 9 (35) | 6 (20) | 6 (13) |
Abbreviations: SD: standard deviation. IQR: inter-quartile range; ESAS: Edmonton Symptom Assessment Scale; MDAS: memorial Delirium Assessment Scale; KPS: Karnofsky performance status; GI: gastrointestinal; GU: genitourinary; GYN: gynecological; H&N: head and neck.
Anova
Chi-square
Kruskal Wallis
ischer exact
For variable Time from cancer diagnosis, the comparison was made with log(time) and therefore Anova test statistic was used.