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. 2018 Mar 2;8:3911. doi: 10.1038/s41598-018-22143-w

Figure 5.

Figure 5

Mahanine modulates sialylation controlling enzymatic activity. (A) Enzyme activities (nmol/min X mg protein) of two representative enzymes (sialidase and sialyltransferase) were determined in the MIAPaCa-2 cell treated with mahanine for 18 hr as described in material and methods. (B) Sialidase and sialyltransferase enzyme activity (nmol/min × mg protein) in the BxPC-3 cells. (C) Relative mRNA level of GD3 synthase gene in MIAPaCa-2 and BxPC-3 cells treated with the increased doses of mahanine for 18 hr.