Table 1.
Criteria | Number |
---|---|
Total no. of SNPs before pruning | 569,244 |
Failed HWE test | 173,955 |
Failed missingness test | 1,934 |
Failed SNP frequency test | 61,167 |
Mendelian errors detected | 349 |
Remaining SNPs after pruninga | 341,191 |
Remaining SNPs refer to those without deviations from Hardy-Weinberg equilibrium (HWE) (p < 0.001), and those having less than 5% missed calls, minor allele frequencies >5%, and Mendelian errors <1%. Note that because some SNPs may fail several criteria, the number of remaining SNPs is not equal to the total number of SNPs minus those removed in the pruning process.