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. 2018 Mar 2;8:3929. doi: 10.1038/s41598-018-22054-w

Figure 9.

Figure 9

Metformin concentrations in liver and tumors measured in mice bearing MDA-MB-231 breast cancer xenografts following treatment with metformin aqueous solution (MH Sol) or metformin-loaded gel (MH Gel) injected s.c. peritumorally. Box-plots include the line at the median, boxes extend from the 25th to 75th percentiles, whiskers show range of data (min to max), a “+” indicates the mean. Results represent the data from individually treated mice (n = 7) (two-sample t-test: *p < 0.05).