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. 2018 Mar 2;8:3907. doi: 10.1038/s41598-018-22326-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Characteristics of MSC-PLT and MSC-FCS. (a) Representative images of MSC-PLT and MSC-FCS showing their morphology and ability to differentiate into adipocytes, osteoblasts and chondroblasts; Scale bars represent 100 or 200 μm; (b) Cumulative population doublings of MSC-PLT and MSC-FCS presented as the mean ± SEM of 13 independent samples; (c) Representative histograms of MSC-PLT and MSC-FCS phenotype showing comparable expression profile of the positive and negative markers.