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. 2018 Mar 2;9(3):353. doi: 10.1038/s41419-018-0383-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Viability of MCF-7 cells treated for 24 h with indicated concentrations of C10 measured by MTT assay (4 independent experiments) and cell counting with trypan blue exclusion (8 independent experiments). The data were calculated as the percentage of the control. b Analysis of cell death by 7AAD assay after treatment for 24 h with indicated inhibitory concentrations (IC) of C10 (13 independent experiments). The data were calculated as the percentage of total cell population. **P < 0.01 and ***P < 0.001 vs. control. c Representative dot plots of granularity analysis by flow cytometry for control cells and cells treated with IC₅₀ of C10 for 24 h (one of 3 independent experiments)