Table 1.
Patient´s Characteristics of 102 Patients Undergoing Radical Cystectomy
| Mannheim Cohort |
MD Anderson Cohort |
P | |||
|---|---|---|---|---|---|
| n or median | percentage/range | n or median | percentage/range | ||
| Age, y | 66.6 | 45.4-92.1 | 67.4 | 41.0-90.6 | 0.72 |
| ≥75 | 21 | 20.6 | 9 | 15.7 | 0.53 |
| <75 | 81 | 79.4 | 48 | 84.2 | |
| Gender | |||||
| Male | 77 | 75.5 | 49 | 86.0 | 0.29 |
| Female | 25 | 24.5 | 8 | 14.0 | |
| Tumor stage | |||||
| pT1 | 2 | 2.0 | 2 | 3.5 | 0.51 |
| pT2 | 24 | 23.5 | 12 | 21.1 | |
| pT3 | 56 | 53.9 | 35 | 61.4 | |
| pT4 | 20 | 19.6 | 8 | 14.0 | |
| CIS | 0 | 0 | 0 | 0 | |
| pT4 or pN+ | 47 | 46.1 | 39 | 68.4 | 0.001 |
| Nodal stage | |||||
| pN0 | 65 | 63.7 | 22 | 38.6 | 0.002 |
| pN1 | 12 | 11.8 | 9 | 15.8 | |
| pN2 | 25 | 24.5 | 26 | 45.6 | |
| Grading | |||||
| G3 | 82 | 80.5 | n.a. | n.a. | |
| G2 | 19 | 18.6 | n.a. | n.a. | |
| G1 | 1 | 0.9 | n.a. | n.a. | |
| Concomitant carcinoma in situ | 23 | 22.5 | n.a. | n.a. | |
| Chemotherapy | |||||
| Neo-adjuvant | 0 | 0 | 20 | 35.0 | <0.001 |
| Adjuvant | 12 | 14.8 | n.a. | n.a. | |
| Outcome | |||||
| Follow-up | 20.8 | 3.6-179.2 | 38.1 | 3.9-180 | 0.63 |
| Cancer-specific death | 50 | 49.0 | 17 | 30.0 | 0.01 |
| Time to Cancer-specific death, months | 17.6 | 3.1-86.5 | 24.2 | 4.8-79.2 | 0.17 |