Fig. 3.
Increased muscle growth in Igf2pA/mG and Zbed6−/− mice. (A and B) Weight of dissected gastrocnemius (gastro), soleus, tibialis anterior, and extensor digitorum longus (EDL) muscles in the indicated genotypes for females (A) and males (B). (C) qPCR analysis of Igf2 mRNA in tibialis anterior muscle. (D) Respiratory exchange ratio (RER) during day and night in single-housed female and male mice with ad libitum access to food. (E and F) Blood glucose after i.p. administration of a glucose bolus and plasma insulin at baseline and 15 min post glucose stimulation in females (E) and males (F). Results are means ± SEM *P < 0.05, **P < 0.01, ***P < 0.001, Student’s t test or two-way ANOVA.