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Efficacy of pembrolizumab, based on RECIST version 1.1 by central imaging vendor review. Data shown are the maximum percentage change from baseline in target lesions (n = 25) (A), change from baseline in tumor size over time (n = 25) (B), treatment exposure and response duration (n = 25) (C), and Kaplan–Meier estimate of overall survival (n = 26) (D). PD, progressive disease; PR, partial response
