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. 2018 Mar 2;12:25. doi: 10.1186/s12918-018-0557-y

Table 2.

Table of antibiotics and the associated genes whose mutations confer antibiotic resistance

Drug Gene iEK1011 reaction Reference
Ethambutol embABC EMB [62]
ubiA DCPT [43]
aftA AFTA [43]
D-cycloserine alr ALAR [63]
ddl ALAALAR [64]
ald ALAD_L, GXRA [44]
Isoniazid katG CAT [65]
inhA FAS [66]
fabG1 MYCSacp56/58/50 [67]
Benzothiazinones dprE1 DCPE [68]
PAS thyA TMDS [51]
ribD FOLR2, ASPRAUR, DHPPDA2 [51]
folC DHFS, THFGLUS [51]
Pyrazinamide pncA NNAM [69]
Ethionamide mshC CIGAMS [52]
Rifampicin drrABC PDIMAT, PPDIMAT [70]