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. 2018 Feb 26;6:46. doi: 10.3389/fpubh.2018.00046

Table 2.

Overview of ECDC- supported laboratory external quality assessments schemes by Disease Programme (DP), target pathogen, testing area and year, 2010–2016.

DPa Pathogen(s) Testing area for assessmentc
Number of EQA exercises/yeard
Detection Typing Virulence/resistance AST Reporting 2010 2011 2012 2013 2014 2015 2016
ARHAI Enterococcus faecalis, E. faecium, E. coli, K. pneumoniae, P. aeruginosa, S. pneumoniae, S. aureus, Acinetobacter spp.b × × × 1 1 1 1 1 1 1
Methicillin-Resistant Staphylococcus aureus × × 1
Clostridium difficile × × 1 1 1
Carbapenemase-producing Enterobacteriaceae × × 1

EVD Hantavirus × 1
Yellow fever viruse × 2
Crimean Congo Hemorrhagic Fever Virus × 1
Tick-borne encephalitis virus × 1
West Nile fever viruse × 2 1
Rift valley fever virus × 1
Dengue virus × 1
Lassa virus × 1
Middle East respiratory syndrome coronavirus × 1
Chikungunya viruse × 2
Zika virus × 1

IRV Human influenza virusf × × × 2 2 2

FWD Salmonella enterica × × 2 1 1 2 1 1
Shiga toxin-producing E. coli × × 2 1 2 1
Listeria monocytogenes × 2 1 1 1
Campylobacter jejuni and C. coli × 1 1
variant Creutzfeldt–Jakob × × 1 1 1 1
Legionella pneumophila × × 4 4 4 4 4

HSH Neisseria gonorrhoeae × × 1 1 1 1 1 1 1

VPD Corynebacterium diphtheriae × × 1 2 1
Neisseria meningitidis × × × 1 1 1 1
Haemophilus influenzae × × × 1 1 1 1
Streptococcus pneumoniae × × × 1 1 1 1
Bordetella pertussis × × 1 2 1 1

TB Mycobacterium tuberculosisg × × × × 2 2 1 2 2 2 2

Total 22 15 19 20 17 13 13

aDP, ECDC Disease Programme; ARHAI, Antimicrobial Resistance and Healthcare-Associated Infections Programme; EVD, Emerging and Vector-borne Diseases Programme; IRV, Influenza and other Respiratory Viruses Programme; FWD, Food and Waterborne and zoonoses Diseases Programme; HSH, HIV, Sexually Transmitted Infections and viral Hepatitis Programme; VPD, Vaccine Preventable Diseases Programme; TB: Tuberculosis Programme.

bEQA cover at least six pathogens included by EARS-Net and resistance phenotypes relevant to the current epidemiology in the EU/EEA.

cDetection: diagnostic test (using culture, molecular, or serological methods) and/or pathogen species identification; Typing: serotyping, molecular, or WGS typing; Virulence/resistance: identification of genetic/phenotypic determinants; AST, Antimicrobial susceptibility testing; Reporting: data analysis and interpretation for reporting according to international/EU case definitions and standard nomenclature.

dFor each pathogen, the number of exercises is dependent on the panel of strains/samples distributed.

eFor these agents, one EQA focused on detection by PCR and another on serology.

fFor influenza virus, one EQA focused on detection by PCR and virus culture with antigenic and genetic characterization and another EQA focused on antiviral susceptibility testing. In addition, WHO provided yearly EQA on PCR detection.

gFor Mycobacterium tuberculosis, one EQA focused on conventional diagnostic tests and another on molecular typing.