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Time course and dose-response measures of in vivo cocaine hydrolysis activity in mice given gene transfer of mutant mouse CocH with different viral vectors. (A) “Standard AAV vector” and (B) high doses of “AAV-VIP” vector. Note the log-linear 10-fold increments of hydrolysis matching the log-linear increments of vector (Geng et al., 2013, Figure 4).
