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. 2018 Feb 27;8:58. doi: 10.3389/fcimb.2018.00058

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Copyright © 2018 Korneev, Kondakova, Sviriaeva, Mitkin, Palmigiano, Kruglov, Telegin, Drutskaya, Sturiale, Garozzo, Nedospasov, Knirel and Kuprash.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LPS from a C. jejuni O2A strain is a moderate inducer of mRNA expression of MyD88-independent proinflammatory chemokines in BMDM. RANTES (A), IP-10 (B), and TNF (C) mRNA levels in BMDM isolated from MyD88^−/−, TLR4^−/− and WT mice. Relative mRNA expression levels were normalized to β-actin. All data are representative of three independent experiments. Data represent mean values ± SD. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, as calculated by two-way ANOVA with Tukey's test for multiple pairwise comparisons. ^#P < 0.01 and ^##P < 0.001 indicates statistically significant LPS activity on WT or MyD88^−/− BMDM vs. TLR4^−/− BMDM.