Table 1.
Overview of the included studies and the results of Jab1/Cops5 inhibitors.
| Name | Indications | Effect | Reference |
|---|---|---|---|
| Thiolutin | Neurospora and HeLa cells | CSN5 activity | Lauinger et al., 2017 |
| Azelaic Acid | Acute Myeloid Leukemia | Protein level | Pan et al., 2017a |
| Azaindoles | HCT116 cells | Protease activity | Altmann et al., 2017 |
| Curcumin | Breast cancer | Protein level | Lim et al., 2016 |
| CSN5i-3 | Various cancer cells | CSN5 activity | Schlierf et al., 2016 |
| Curcumin analog T83 | Nasopharyngeal carcinoma | Protein level | Pan et al., 2013a |